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10 Best Cold Sore Treatments 2025 in the UK

#1

Winner

9.9 score

Compeed Cold Sore Discreet Healing Patch, 15 Count (Pack of 1)

Active Ingredients: hydrocolloid
Form of Treatment: Patch
Application Frequency: up to 12 hours
Speed of Relief: faster healing

Chosen by 1277 this week

Zovirax Cold Sore Treatment Cream, Pump Dispenser, 2 g, packaging may vary

Active Ingredients: 5% w/w Aciclovir
Form of Treatment: Cream
Application Frequency: Four times daily
Speed of Relief: Healing time is four days
Side Effects: Minimal
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Our Top Picks

#1

Winner

Compeed Cold Sore Discreet Healing Patch, 15 Count (Pack of 1)

Rating
9.9
Chosen by1,277
Application Frequency
Speed of Relief
Application Frequency
Using the patches religiously day and night led to a cold sore being nearly gone within a few days, even without other treatments.
Speed of Relief
It stays put all day and night without budging if applied correctly, acting as a protective layer that drastically speeds up healing time.

The Compeed Cold Sore Discreet Healing Patch offers a modern and convenient way to manage cold sores. Its main active ingredient, hydrocolloid, is effective in creating a moist environment that promotes faster healing and reduces scab formation. This is particularly beneficial for people looking for a quick remedy, as it can speed up the healing process significantly. The patch acts as a protective shield, helping to reduce the risk of contamination from external elements. It's designed to stay put for up to 12 hours due to its adhesive and tapered edges, which means less frequent application and more comfort throughout the day.

One of the major draws of the Compeed patch is its discreet nature. Being translucent, it can blend in with the skin, thus minimizing any social discomfort or embarrassment caused by visible sores. This is appealing for users who are conscious about appearance during outbreaks. Another advantage is its ease of use, thanks to the new applicator design, although users are advised to be careful when applying.

However, it's essential to consider that the patch is primarily designed for external protection and moisture retention, rather than delivering medicinal ingredients directly to the sore. Therefore, for those seeking a more aggressive treatment with antiviral properties, this might not meet their expectations. Additionally, while the patch provides comfort and protection, its effectiveness can vary among individuals depending on the severity of the outbreak. No significant side effects have been reported, making it a generally safe option for all age groups.

In essence, this product is well-suited for those who prefer a non-invasive, protective measure that aids the natural healing process of cold sores, especially for those prioritizing discretion and convenience.

Rating
9.9
Chosen by1,277
Application Frequency
Speed of Relief
Application Frequency
Using the patches religiously day and night led to a cold sore being nearly gone within a few days, even without other treatments.
Speed of Relief
It stays put all day and night without budging if applied correctly, acting as a protective layer that drastically speeds up healing time.
#2

Zovirax Cold Sore Treatment Cream, Pump Dispenser, 2 g, packaging may vary

Rating
9.8
Form of Treatment
Speed of Relief
Form of Treatment
The cream is easy to carry and apply discreetly, fitting conveniently in your bag for use on-the-go.
Speed of Relief
When applied at the first sign of a cold sore, this cream keeps it small and unnoticeable, preventing it from becoming a huge bump.

Zovirax Cold Sore Treatment Cream is designed for adults dealing with cold sores. The active ingredient, aciclovir, is known for its antiviral properties, which help to shorten the duration of pain and speed up healing. This cream comes in a convenient pump dispenser, making it easy to apply directly to the affected area.

One of its standout features is that it can start working at the initial tingle phase as well as during the blister stage, potentially reducing the cold sore's duration to as few as three days for some users, though the median healing time is four days. This could be particularly beneficial for anyone looking for rapid relief from discomfort and visible sores. However, the treatment needs to be applied frequently—four times daily—which might be inconvenient for some users. It's crucial to follow the application instructions for optimal results.

Side effects are minimal but, like any medication, there is always a possibility for individual reactions. Its fast-acting nature and ability to reduce pain duration are strong points, making it a popular choice. The cream's small size (2 grams) also makes it easy to carry around. On the downside, frequent application and the relatively small quantity could be considered minor drawbacks. In summary, Zovirax Cold Sore Treatment Cream is a well-regarded and effective option for those looking to quickly manage and heal cold sores.

Rating
9.8
Form of Treatment
Speed of Relief
Form of Treatment
The cream is easy to carry and apply discreetly, fitting conveniently in your bag for use on-the-go.
Speed of Relief
When applied at the first sign of a cold sore, this cream keeps it small and unnoticeable, preventing it from becoming a huge bump.

Buying Guide for the Best Cold Sore Treatments

Cold sores, also known as fever blisters, are caused by the herpes simplex virus. They can be painful and unsightly, but there are various treatments available to help manage symptoms and speed up healing. When choosing a cold sore treatment, it's important to consider the type of treatment, its effectiveness, and how it fits into your lifestyle and needs. Here are some key specifications to look for when selecting a cold sore treatment.
Active IngredientsActive ingredients are the components in a treatment that help to alleviate symptoms and promote healing. Common active ingredients in cold sore treatments include acyclovir, docosanol, and benzyl alcohol. Acyclovir and docosanol are antiviral agents that can help reduce the duration and severity of cold sores, while benzyl alcohol can provide pain relief. If you frequently get cold sores, you might want to choose a treatment with a strong antiviral ingredient. If pain is your main concern, look for treatments with pain-relieving ingredients.
Form of TreatmentCold sore treatments come in various forms, including creams, gels, patches, and oral medications. Creams and gels are applied directly to the sore and can provide targeted relief. Patches can cover the sore, protect it from further irritation, and deliver medication over time. Oral medications are usually prescribed for more severe cases and work systemically to combat the virus. Consider your lifestyle and preferences when choosing the form of treatment. If you need discreet and continuous relief, patches might be ideal. If you prefer direct application, creams and gels are a good choice.
Application FrequencyThe frequency with which you need to apply the treatment can vary. Some treatments require application several times a day, while others might only need to be applied once or twice. Treatments that need frequent application can be more effective but may be less convenient if you have a busy schedule. If you can commit to regular application, you might benefit from treatments that require frequent use. If you need something more convenient, look for treatments with less frequent application requirements.
Speed of ReliefThe speed at which a treatment provides relief can be crucial, especially if you need to reduce symptoms quickly for an upcoming event or to minimize discomfort. Some treatments start working within hours, while others may take a day or two to show effects. If you need fast relief, look for treatments that are known for their quick action. If you can afford to wait a bit longer for relief, you might have more options to choose from.
Side EffectsSide effects are unwanted reactions that can occur with any medication. Common side effects of cold sore treatments can include skin irritation, dryness, or allergic reactions. It's important to read the label and understand the potential side effects before choosing a treatment. If you have sensitive skin or are prone to allergies, look for treatments with minimal side effects. If you are generally tolerant of medications, you might be able to use stronger treatments without issue.